This unique resource will provide a practical and thorough vision on the most recent trends in plasmonic optical fiber biochemical sensing. This book gathers up-to-date technological information, and shows the maturity reached by the different subsequent technologies to experiment practical implementations. Plasmonic optical biosensors allow label-free and highly sensitive detection of analytes, usually within a dedicated microfluidic system that brings the sample to the biosensor surface. Compared to the bulky Kretschmann prism configuration implemented in most commercial systems, an optical fiber has been developed to improve measurements in a miniaturized system. Demonstrating roadmaps for the design process and practical implementation of plasmonic optical fiber biochemical sensors, this book helps the reader understanding the role of the fiber configuration and the functional coating in the fundamental properties of the derived optrodes. The book bridges the gap between theory and application of plasmonic optical fiber biosensors and highlights their main properties. Understanding these key physical properties is of paramount importance for the efficient design of sensing platforms that will meet the target specifications.